Buy Hydrocodone Online with Prescription. Pillsambien pharmacy, secure checkout, discreet shipping, and fast home delivery. Order Now Hydrocodone is a prescription opioid medication widely used for the short-term management of moderate to severe pain. When pain cannot be adequately controlled with non-opioid treatments, healthcare providers may prescribe hydrocodone—often in combination with acetaminophen—to help patients regain comfort and function.